U 48800 Research Chemical Powders , Analgesic Opioid Research
Chemicals CAS 82657-23-6
U-48800 U48800 Powder
U-48800 is an opioid analgesic drug developed by a team at Upjohn
in the 1970s that acts as a selective agonist of the µ-opioid
receptor with a Kd value of 5.3 nM compared to 910 nM for the
κ-opioid receptor and has around 7.5 x the potency of morphine in
U-48800 is a structural isomer of the earlier and the result of a
great deal of work elucidating the quantitative structure–activity
relationship of the scaffold.
Upjohn looked for the key moieties which gave the greatest activity
and posted over a dozen patents on related compounds, each
optimizing one moiety until they discovered that U-48800 was the
U-48800 became the lead compound of selective kappa-opioid receptor
ligands such as (containing a single methylene spacer difference)
and U-69,593, which share very similar structures.
Although not used medically, the selective kappa ligands are used
Systematic (IUPAC) name:
1. Samples are provided for test;
2. Good quality products;
3. 100% secure delivery.
Payment ways: Western Union, Moneygram, Bitcoin, T/T
Delivery: EMS/ EUB/ USPS/ UPS/ TNT/ FEDEX/ DHL etc
Packaging: safe and discreet packaging
Dongmao Biotechnology Co., Limited specializes in exporting high
quality Research chemical, medical intermediate, Pharmaceutical
chemicals and so on.
Our products are produced on the basis of best technical team,
advanced equipment, high qualified management which meet the
requirements of security and environmental protection. We earned
customer trust and created a good reputation during these years. we are committed to provide the excellent quality of products and
the perfect services to the friends all over the world.
We will provide the most comprehensive products and service to you!
We are looking forward to your cooperation.
1. How is the quality?
The qualities of most products are above 99% purity, same are 99.7%
2. How is the package?
Aluminum foil bag or as customer's required.
3. How is the storage?
Keep in dry and cool place.
4. Do I need to pay extra for shipping cost?
No, our price includes the shipping cost already; you need not pay
for any tax and others.
5. Can I order sample to test?
Yes, you are welcome to order sample before placing bulk order. We
will send the sample directly to your door by courier.